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Generic Cialis (Tadalafil)
Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Adcirca) is used to improve the ability to exercise in people with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works to treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily.
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Common use
Cialis is an effective, reversible, selective
inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic
guanosine monophosphate (cGMP). When sexual stimulation causes local
release of nitric oxide, inhibition of PDE 5 by Cialis leads to increase
of cGMP levels in the cavernous body of penis. It results in relaxation
of arterial smooth muscles and blood flow to the tissues of the penis
that causes erections. Cialis has no effect when sexual stimulation is
absent. Cialis improves erection and lets achieve a successful sexual
intercourse. The drug acts during 36 hours. If sexual arousal is present
the effect appears even after 16 minutes after the medication was
taken.
Dosage and direction
The recommended dose of Cialis
is 20 mg it should be taken at least 16 minutes before the sexual
activity. The effect persists during 36 hours. Take Cialis once daily
and do not exceed the recommended dose.
Precautions
It is
preferable not to use Cialis with grapefruit juice, alcoholic beverages,
tobacco. If you smoke tobacco and take Cialis concomitantly this may
lead to a condition called NAION (sudden optic nerve-related vision
loss). Inform your doctor before to take Cialis if you have abnormal
penis, including curved penis and birth defects of the penis, had
coronary artery disease, arrhythmia, angina, heart attack or heart
failure, hypo- or hypertension, bleeding, stomach ulcers, diabetes,
hyperlipidemia (excess of lipids in the blood), sickle-cell anemia,
liver or kidney failure in history.
Contraindications
Cialis
is contraindicated in patients who are using any form of organic
nitrate, either regularly and/ or intermittently as it is able to
potentiate hypotensive effect of nitrates.
Possible side effects
Most
usual side effects of Cialis are facial flushing (reddening),
headaches, stomach upset, diarrhea, flu-like symptoms and nausea. In
more rare cases low blood pressure, blurred vision and changes in color
vision, and abnormal ejaculation may occur. Prolonged erections or
priapism (painful erections lasting more than 6 hours) are also
possible. If your erection is longer than 4 hours, seek for immediate
medical help as it may permanently damage your penis. Aggravation of
heart problems in patients with pre-existing heart disease using Cialis
was reported.
Drug interactions
Co-administration with
medications containing organic nitrates may cause severe hypotension
which is dangerous in some cases. Avoid taking Calis with medications
such as Erythrityl Tetranitrate, Isosorbide Dinitrate, Isosorbide
Mononitrate, Nitroglycerin, Pentaerythritol Tetranitrate. Levels and
toxicity of Cialis are increased by erythromycin, ketoconazole
(Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir
(Norvir). Inform your doctor if you are taking Atazanavir, Bunazosin,
Clarithromycin, Doxazosin, Erythromycin, Indinavir, Itraconazole,
Ketoconazole, Moxisylyte, Nefazodone, Nelfinavir, Phenoxybenzamine,
Phentolamine, Prazosin, Saquinavir, Telithromycin, Terazosin,
Trimazosin, Urapidil as your Cialis dose may require correction.
Missed dose
Missed
dose is not supposed if Cialis is taken for treatment of erectile dysfunction as it s used
when needed.
Overdose
Overdose
of Cialis causes symptoms described as side effects. Seek for immediate
medical help if you by your opinion you took too much of this
medication.
Storage
Store at room temperature away from moisture, sunlight,
kids and pets in a tight container.
Disclaimer
We
provide only general information about medications which does not cover
all directions, possible drug integrations, or precautions. Information
at the site cannot be used for self-treatment and self-diagnosis. Any
specific instructions for a particular patient should be agreed with
your health care adviser or doctor in charge of the case. We disclaim
reliability of this information and mistakes it could contain. We are
not responsible for any direct, indirect, special or other indirect
damage as a result of any use of the information on this site and also
for consequences of self-treatment.